The authorized source of trusted medical research and education for the Chinese-language medical community. KDIGO clinical practice guideline for acute kidney injury. Section 2: AKI definition
At 10 years, the hazards for mortality ranged from 1.15 (for mild AKI) to 1.33 (for severe AKI). 5 Similar findings were observed among 87 094 Medicare patients admitted to US hospitals between 1994 and 1995 9 and in the Survival and Ventricular Enlargement (SAVE) trial. 7 A large meta-analysis of 48 studies comprising 47 017 patients
The current definition of microalbuminuria (MA) is an amount of urinary albumin greater than the normal value but also lower than what is detected by a conventional dipstick. Thus, the rate of urine albumin excretion (UAE) in microalbuminuria is 30 to 300 mg/24 hours. In other units, it can also mean 30–300 mcg/mg creatinine or 20–200 mcg
In a multicenter study of patients presenting to the emergency department with suspected sepsis, pNGAL strongly predicted AKI with an AUC of 0.82 versus 0.73 for creatinine. 11 However, only 1.7% of subjects developed AKI based on the study definition, and serum creatinine was higher (1.9 mg/dL) in those with AKI compared with those without (1.
In 2009, another creatinine-based definition of AKI was proposed on the rationale that the amount of time needed to reach a relative change in creatinine (for example, a 50% increase or a 100%
In recent years, diagnostic criteria have been proposed for the diagnosis of ARF in non-cirrhotic patients, now termed AKI. In particular, two separate bodies developed and published two consensus definitions of AKI: the Acute Dialysis Quality Initiative group for the Risk, Injury, Failure, Loss of Renal Function and End-Stage Renal Disease (RIFLE) criteria; and the Acute Kidney Injury Network
Acute kidney injury means your kidneys stop working suddenly. AKI requires immediate treatment and may be reversible if diagnosed and treated quickly—unlike chronic kidney disease (CKD), which is kidney damage that typically progresses slowly over a period of time and is not reversible. Some people diagnosed with AKI will need temporary
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aki in medical terms
